Determinant via column operations

Consider the real matrices $$A=\begin{pmatrix}a&3d&3\\b&3e&-2\\c&3f&1\end{pmatrix},\quad B=\begin{pmatrix}a&b&c\\1&-3&5\\2d&2e&2f\end{pmatrix},\quad C=\begin{pmatrix}a&b&c\\d&e&f\\-1&-4&9\end{pmatrix}.$$ If the determinant of $A$ is $-48$ and the determinant of $B$ is $2$, then the determinant of $C$ equals __________ (in integer)